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Express Screening Test for detection
of diseases at an early stage


A unique express screening test that has no analogues in the world that identifies:
  • oncology at an early stage
    (when there are no symptoms or clinical manifestations)
  • the most common somatic diseases
    (diabetes, cardiovascular pathologies, fibrocystic diseases)
Blood sample from a blood vessel
Data processing (equipment + software)


Low cost - $30
15 minutes to obtain a diagnostic report
Detection of diseases at an asymptomatic stage, when there is still a high probability to prevent the development of the disease.
GOAL:
Increase screening adherence by making screening more accessible.
TASK:
Venous blood (1 tube)
MATERIAL:
Infrared spectroscopy (IR spectroscopy)
METHOD:
CONCEPT
There is no blueprint for putting an end to cancer. That's why we're focused on developing accessible test to detect cancer in its earliest, most treatable stages (1&2).
Why our screening test is prospective?
example: oncology
  • 20 000+
    Clinically graded patients (tests)
  • ±96%
    Test accuracy
  • 5+ years
    Project development
  • 70%
    Types of oncology, determined by test
Obtaining an IR spectrum of the patient's blood
The use of modern Fourier spectrometers allows you to instantly record the IR spectra of a patient's blood. The devices have a high degree of accuracy.
Collection of venous blood to obtain the infrared spectrum. The IR spectrum represents the dependence of the intensity of absorption of IR radiation by a substance on the vibration frequency. The higher the concentration of a substance in the blood, the greater the intensity of absorption of IR radiation by the substance. By changing the intensity of absorption, you can determine the relative change in the concentrations of metabolites in the blood.
Sample preparation
The Fourier spectrometer is equipped with built-in software that allows you to transform graphic information into a digital series.
Mathematical data processing
1
2
3
IR spectroscopy
is a method for studying substances based on the absorption of infrared (IR) radiation by the substance under study.
The presence of our own unique software, developed on a reliable database consisting of more than 20,000 clinically verified patient data, allows us to obtain diagnostic conclusions for a large number of patients at once in real time.
Issuance of a diagnostic report


4
METHOD DESCRIPTION
Using an IR spectrometer and specially developed algorithms and software, blood is analyzed and shifts in the metabolism of metabolites are identified.
How it works
1
2
3
Tested Cancer Types
  1. Lung cancer
  2. Oesophagus cancer*
  3. Stomach cancer
  4. Colorectum cancer
  5. Thyroid cancer*
  6. Prostate cancer
  7. Breast cancer
  8. Uterine cancer
  9. Cervix uteri cancer
  10. Ovarian cancer
  11. Kidney cancer
  12. Bladder cancer
  13. Hematologicalcancer
New cancer cases worldwide, 2020
Заболеваемость раком в мире в 2020 году (чел.)
±70% от мировой статистики по распространенности
±70% от мировой статистики по распространенности
* On development stage
** All other types are rare types of oncology
70% of world statistics
Tested Somatic Diseases
Cardiovascular pathologies


First place in the world in mortality
(coronary heart disease, chronic heart failure, heart defects)


Diabetes
9th highest mortality rate in the world


Fibrocystic disease of breast and genitals
High probability of degeneration into oncology
Prostate pathology
50% of the male population experiences manifestations of prostate adenoma and prostatitis during their lifetime
Gastritis
Gastric ulcer and duodenum
Cholecystitis
Pancreatitis
"Diseases of the century"
(stress, unhealthy diet, overwork)
Scientific Substantination of the Method
Changes in the parameters of the IR spectra, corresponding to changes in the relative concentrations of metabolites in the blood of patients, act as diagnostic markers - predictors of diseases, since with any metabolic disorder caused by pathology, the ratios of metabolites of carbohydrate, protein and lipid metabolism are disrupted.

IR spectroscopy with high precision, at the nanolevel, allows you to identify these changes at the earliest stages of the disease, while the clinical picture has not yet been formed, and also allows you to evaluate the effectiveness of the therapeutic or surgical treatment.

The scientifically proven accuracy of IR spectroscopy allows the method to be used as a diagnostic technique for screening diagnostics of oncological diseases:
  • 86%
    SENSITIVITY
    86,6%
    (±6,2%)
  • 97%
    SPECIFITY
    97,6%
    (±1,2%)
  • 96%
    ACCURACY
    96% (±11,4%)
Advantages
Efficiency
High diagnostic accuracy, simultaneous diagnosis of several types of pathologies (no need to examine each organ separately), especially oncology - all this combined with short testing time (no more than 15 minutes).

Diagnosing oncology in the early stages
As a rule, cancer at stages I and II is discovered by chance (for example, during an ultrasound or x-ray), since neither at stages I nor II a person feels any changes in his health - there is no weakness, no pain. Our screening test allows to determine oncology already at stage I with an accuracy of 87%-95%.
Covering more than 70% of oncology types,
that is, 13 types of oncology, which are the most common according to statistics in the world. At the same time, the versatility of the technique allows us not to be limited to 13 types of cancer and to develop the method further, as well as the most common somatic diseases in terms of mortality (cardiovascular pathologies, diabetes).
Low cost of the test - $30
The analysis uses only special equipment and there are no biochemical reagents. Accordingly, the formation of a lower selling price compared to tumor markers, for which only 1 type of cancer costs from $60 to $200.
Easy to transport and store analysis
After collection, venous blood undergoes special sample preparation, as a result of which it is dried and, already in dry form, can be transported to the master laboratory from cities and countries of different distances.
No negative effects
on the body (irradiation).
The uniqueness of the method
Lack of analogues in the field of medicine
Ease of execution
The availability of modern equipment and software allows laboratory assistants to prepare samples for testing.
  • Compulsory health insurance

  • Risk groups monitoring (older age)

  • Additional diagnostic tool (private clinics and laboratories)

  • Insurance companies (testing for signs that increase mortality risk)
▪ Evaluation of treatment effectiveness

▪ Relapse detection

▪ Determination of target organs to which metastases are directed

▪ Assessment of health condition after chemotherapy
BEFORE diagnosis is made
AFTER diagnosis is made
▪Computed tomography of the lungs and kidneys - $170
▪ Fibrogastroduodenoscopy - $370
▪ Sigmoidoscopy - $270
▪ Colonoscopy - $170
▪ Cystoscopy - $755
▪ General blood analysis - $12
▪ Blood test for serum biochemical tumor markers - $340


One screening test
to detect diseases at the asymptomatic stage
Existing diagnostic methods
Our screening test
  • Компьютерная томография легких и почек - до 15 тыс.руб.

  • Фиброгастродуоденоскопия - до 33 тыс.руб.

  • Ректороманоскопия - до 24 тыс.руб.

  • Колоноскопия - до 15 тыс.руб.

  • Цистоскопия - до 67 тыс.руб.

  • Общий анализ крови - до 1 тыс.руб.

  • Исследование крови на сывороточные биохимические

    онкомаркеры - до 30 тыс.руб.


  • Компьютерная томография легких и почек - до 15 тыс.руб.

  • Фиброгастродуоденоскопия - до 33 тыс.руб.

  • Ректороманоскопия - до 24 тыс.руб.

  • Колоноскопия - до 15 тыс.руб.

  • Цистоскопия - до 67 тыс.руб.

  • Общий анализ крови - до 1 тыс.руб.

  • Исследование крови на сывороточные биохимические

    онкомаркеры - до 30 тыс.руб.


Past
Future
Один скрининг-тест по выявлению заболеваний на бессимптомной стадии
for $30
  • Компьютерная томография легких и почек
    до 15 тыс.руб.

  • Фиброгастродуоденоскопия
    до 33 тыс.руб.

  • Ректороманоскопия
    до 24 тыс.руб.

  • Колоноскопия
    до 15 тыс.руб.

  • Цистоскопия
    до 67 тыс.руб.

  • Общий анализ крови
    до 1 тыс.руб.

  • Исследование крови на сывороточные биохимические
    онкомаркеры
    до 30 тыс.руб.


Women:

  • Mammography – $250

  • Ultrasound of the breast - $23

  • Ultrasound of the uterus and cytological examination of

    scrapings from cervix - $15


Men:

• Ultrasound of the prostate gland - $23
Мужчины:

  • • УЗИ предстательной железы - 2 тыс.руб.

(depending on gender)
From $2 000 to $2 400
(в зависимости от пола)
+
The screening test we created is a breakthrough technology in the field of MedTech.

Digital automatic processing allows mass screening diagnostics, which significantly increases the efficiency of medical care and contributes to the digitalization of medicine.
Prospectives
Project Team
  • Shaimbetov B.
    Deputy Director for Scientific Work at the Oncology Center, Doctor of Medical Sciences, Professor
  • Toygonbekov A.
    Head of the Department of Abdominal Oncology at the Oncology Center, Doctor of Medical Sciences
  • Beishembaev M.
    Head of the Department of Thoracic Oncology at the Oncology Center, Doctor of Medical Sciences, Professor
  • Osombaev M.
    Head of the Department of Oncoproctology at the Oncology Center, Candidate of Medical Sciences, Associate Professor
  • Aralbaev R.
    Head of the Department of Radiation Therapy at the Oncology Center, Doctor of Medical Sciences, Professor
Contacts
hello@topscreening.com
SIA «DEXTRO», Latvia, Jurmala